STUDY:  In deep second and third degree burns the trial will test the clinical efficacy of MicroSurfaced Cadaveric Grafts to establish burn wound healing in partial-thickness burns and wound bed preparedness for transfer of autologous skin in deep-partial and full-thickness burn wounds as compared to Control Smooth Cadaveric Grafts over a 6-week treatment period.  Clinicaltrials.gov Identifier: NCT04589442 

Histologic Evaluation of Wound-Bed Preparedness Following Microsurfaced Skin Grafts for the Treatment of Deep Burn Wounds: Results from a Randomized Controlled Trial.

Lisa M. Marinelli MD; Kevin Krauland MD, Department of Pathology and Area Laboratory Services, Brooke Army Medical Center, Fort Sam Houston, TX 

CONCLUSION: Microsurfaced skin grafts resulted in consistent incorporation and greater cellular infiltration and graft thickness than their control graft counterparts, a finding we attribute to increased surface area at the graft-to-host interface.

Human Clinical Trials: PHASE 1

DENTAL SURGERY

STUDY: The objective of this trial is to evaluate clinical healing outcomes of Microsurfaced cadaveric ADM (Acellular Dermal Matrix) used in sites with gum recession  as compared to control cadaveric Smooth ADM. Clinicaltrials.gov Identifier: NCT04614350 

Note: This study is to be published in the International Journal of Periodontics and Restorative Dentistry in fall 2024.